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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITSN1
All Species:
20
Human Site:
S777
Identified Species:
55
UniProt:
Q15811
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15811
NP_001001132.1
1721
195422
S777
K
G
E
W
V
D
E
S
Q
T
G
E
P
G
W
Chimpanzee
Pan troglodytes
XP_001166935
1721
195424
S777
K
G
E
W
V
D
E
S
Q
T
G
E
P
G
W
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848967
1721
195215
S777
K
G
E
W
V
D
E
S
Q
T
G
E
P
G
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0R4
1714
194267
S770
D
I
V
M
V
D
E
S
Q
T
G
E
P
G
W
Rat
Rattus norvegicus
Q9WVE9
1217
137136
E380
E
Q
Q
R
K
E
Q
E
R
L
A
Q
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512411
1723
194923
D775
M
V
K
G
V
W
V
D
E
S
Q
T
G
E
P
Chicken
Gallus gallus
XP_416715
1716
194993
S774
K
R
E
W
V
D
E
S
Q
T
G
E
P
G
W
Frog
Xenopus laevis
O42287
1270
143652
E433
R
K
E
I
E
R
R
E
A
A
K
R
E
L
E
Zebra Danio
Brachydanio rerio
NP_997065
1721
194097
S734
D
I
V
M
V
D
E
S
Q
T
G
E
P
G
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
97.2
N.A.
94.5
65.4
N.A.
90
92.9
60.5
77.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
98.7
N.A.
96.8
67.7
N.A.
93.8
96.2
66.3
85.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
73.3
0
N.A.
6.6
93.3
6.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
73.3
40
N.A.
26.6
93.3
13.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
12
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
0
0
0
0
67
0
12
0
0
0
0
0
0
0
% D
% Glu:
12
0
56
0
12
12
67
23
12
0
0
67
12
23
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
34
0
12
0
0
0
0
0
0
67
0
12
67
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
23
0
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
45
12
12
0
12
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
12
0
0
12
12
0
% L
% Met:
12
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
12
% P
% Gln:
0
12
12
0
0
0
12
0
67
0
12
12
0
0
0
% Q
% Arg:
12
12
0
12
0
12
12
0
12
0
0
12
0
0
12
% R
% Ser:
0
0
0
0
0
0
0
67
0
12
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
67
0
12
0
0
0
% T
% Val:
0
12
23
0
78
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
45
0
12
0
0
0
0
0
0
0
0
67
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _